At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 220 enrolled
Drug / intervention
Processed Nerve Allograft (human) +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Multicenter, Prospective, Randomized, Subject and Evaluator Blinded Comparative Study of Nerve Cuffs and Avance® Nerve Graft Evaluating Recovery Outcomes for the Repair of Nerve Discontinuities
In Brief
A Phase 3 clinical trial evaluating Processed Nerve Allograft (human) and Collagen Nerve Cuff for Peripheral Nerve Discontinuities. Completed, enrolled 220 participants across 21 sites.
Detailed Summary
Processed Nerve Allograft and Collagen Nerve Cuffs will be compared to assess safety and functional outcomes for the repair of nerve injuries in the hand.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeripheral Nerve Discontinuities
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 2013
Enrollment StartJun 2015
Primary CompletionAug 2021
TodayJul 2026
First PostedMar 12, 2013
Enrollment StartJun 1, 2015
Primary CompletionAug 30, 2021
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 13.3 years ago
Interventions
Processed Nerve Allograft (human)biological
Collagen Nerve Cuffdevice
Bovine collagen based nerve cuff