At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 684 target
Drug / intervention
Sevoflurane +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Total Intravenous Anesthesia With Sevoflurane-based Balanced Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients for Major Elective Intra-abdominal Surgery
In Brief
A Phase 4 clinical trial evaluating Sevoflurane, propofol, and 1 other intervention for Intra-abdominal and Intrapelvic Surgery. Completed, enrolled 684 participants across 1 site.
Detailed Summary
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Most patients will receive general anesthesia during surgery. Two groups of general anesthetics are used for this purpose. We hypothesize that the incidence of POCD is not different in patients received intravenous anesthetics only or sevoflurane (a volatile anesthetic-based general anesthesia) for their major intra-abdominal surgery.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntra-abdominal and Intrapelvic Surgery
CountriesChina
CollaboratorsFirst Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Huaqiao Hospital in Guangzhou, China, First People's Hospital of Foshan, Nanfang Hospital, Southern Medical University, Guangdong Provincial People's Hospital, China, Baxter (China) Investment Co. Ltd.
Timeline
Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
Enrollment StartMar 2013
First PostedMar 2013
Primary CompletionApr 2019
TodayJul 2026
First PostedMar 12, 2013
Enrollment StartMar 1, 2013
Primary CompletionApr 1, 2019
TodayJul 2, 2026
Enrollment to primary: 6.1 yearsPosted 13.3 years ago
Interventions
Sevofluranedrug
propofoldrug
remifentanildrug