CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 53 enrolled
Drug / intervention
Dexamethasone +1 moredrug
Likely dose
Dexamethasone 8 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01812057
NCT01812057Phase 4Completed
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Dexamethasone as an Analgesic Adjunct for Post-cesarean Delivery Pain Relief

Duke University·interventional·Posted Mar 15, 2013·Updated Jul 25, 2017

In Brief

A Phase 4 clinical trial evaluating Dexamethasone and Placebo for Pain, Postoperative and Postoperative Nausea and Vomiting. Completed, enrolled 53 participants across 1 site.

Detailed Summary

The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative steroid (dexamethasone 8 milligrams) versus placebo at 24 hours after surgery. The hypothesis is that a single perioperative dose of dexamethasone 8 mg will significantly reduce postoperative opioid consumption at 24 h in women having cesarean delivery under spinal anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative, Postoperative Nausea and Vomiting
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 15, 2013
Enrollment StartDec 1, 2012
Primary CompletionMay 27, 2016
Study CompletionSep 21, 2016
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 13.3 years ago

Interventions

Dexamethasonedrug

Dexamethasone 8 mg IV (as a one time dose)

Placebodrug

Sodium Chloride 0.9% -5 ml