CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 474 enrolled
Drug / intervention
2% mupirocin ointment +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01814371
NCT01814371N/ACompleted
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Individualized vs. Household Eradication of MRSA in Households With Children

Washington University School of Medicine·interventional·Posted Mar 19, 2013·Updated Feb 21, 2019

In Brief

A clinical study evaluating 2% mupirocin ointment, Bleach Bath (dilute), and 1 other intervention for Staphylococcal Skin Infection and 4 related conditions. Completed, enrolled 474 participants across 1 site.

Detailed Summary

The purpose of this research study is to compare the effectiveness of commonly used decolonization treatments (application of mupirocin antibiotic ointment to the nose and bleach baths) when performed by individuals with a history of skin and soft tissue infection (SSTI) in the prior year (individualized approach) in comparison to decolonization of all household members (household approach) in an attempt to prevent Staphylococcus aureus skin infections. The investigators hypothesize an individualized decolonization approach will be equally as effective as a household approach to prevent SSTI.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStaphylococcal Skin Infection, Abscess, Furunculosis, Staphylococcus Aureus, MRSA Infection
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 19, 2013
Enrollment StartApr 1, 2013
Primary CompletionFeb 26, 2017
Study CompletionNov 28, 2017
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 13.3 years ago

Interventions

2% mupirocin ointmentdrug

Participants over 1 month of age, apply ointment to the anterior nares twice daily for 5 days.

Bleach Bath (dilute)other

Participants over 1 month of age, pour 1/4 cup of bleach into a bath tub filled 1/4 full of water. Soak in bath for 15 minutes daily for 5 days.

Hygiene Protocolbehavioral

Follow key hygiene tips: * Throw out all lotions or creams that you dip your hands into and replace with pumps or pour bottles. * Use liquid(pour or pump) soaps instead of bar soaps. * Wash hands frequently or use hand sanitizer(with more than %60 alcohol) such as Germ-X or Purell. * Do not share personal care items such as razors, brushes, or deodorant. * Wash all sheets and towels in hot water. Wash sheets every week. * Use towels and wash cloths only once before washing and do not share.