CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 308 enrolled
Drug / intervention
Lidocaine hydrochloride (HCl) 1% solution +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01814657
NCT01814657N/ACompleted

Optimizing Patient Analgesic Experience During IVF

University of Alberta·interventional·Posted Mar 20, 2013·Updated Jul 18, 2022

In Brief

A clinical study evaluating Lidocaine hydrochloride (HCl) 1% solution and Sterile Normal Saline% for Infertility. Completed, enrolled 308 participants across 1 site.

Detailed Summary

This study is for patients undergoing In Vitro Fertilization (IVF). The investigators are studying the best way to control pain during the egg retrieval process. The egg retrieval involves passing a needle under ultrasound guidance through the vagina into the ovaries to remove eggs that are to be later fertilized. Patients often report this as very uncomfortable. Different fertility clinics across the country use different methods of pain control. All clinics will use intravenous medication to control pain, while some may or may not use local anaesthetic (freezing) in the vagina. Our goal is to find the best way to control pain. Since local anaesthetic injection involves multiple needle punctures and may be painful, the investigators are unsure if local anaesthetic is necessary in addition to the intravenous pain medication. The investigators will conduct a randomized trial where all patients will receive intravenous pain medication, but some will receive local anaesthetic injection and some will receive placebo injection. Patients will be asked to complete a questionnaire on their pain experience after oocyte retrieval. The investigators will then analyze the data and determine whether local anaesthetic actually improves pain when patients are already receiving intravenous pain medications. Through our study, the investigators aim to improve the pain experience of all women undergoing IVF in the future.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfertility
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 20, 2013
Enrollment StartMar 1, 2013
Primary CompletionNov 7, 2015
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 13.3 years ago

Interventions

Lidocaine hydrochloride (HCl) 1% solutiondrug

Comparison of paracervical block using Lidocaine versus Normal Saline placebo in patients undergoing oocyte retrieval during IVF.

Sterile Normal Saline%drug

Sterile normal saline used as placebo for lidocaine hydrochloride (HCl)1% solution