CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 177 enrolled
Drug / intervention
Chlorhexidine Gluconate Skin Cleanser +3 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01817075
NCT01817075Phase 3Completed
CompareCT.gov

Impact of Cleansing With Chlorhexidine Gluconate (CHG) on Reducing Central Line Associated Bloodstream Infection (CLABSI) and Acquisition of Multi-drug Resistant Organisms (MDRO) in Children With Cancer or Those Receiving Allogeneic Hematopoietic Cell Transplantation (HCT)

Children's Oncology Group·interventional·Posted Mar 22, 2013·Updated Jun 22, 2021

In Brief

A Phase 3 clinical trial evaluating Chlorhexidine Gluconate Skin Cleanser, Laboratory Biomarker Analysis, and 2 other interventions for Bacterial Infection and 6 related conditions. Completed, enrolled 177 participants across 59 sites in 3 countries.

Detailed Summary

This randomized phase III trial studies chlorhexidine gluconate cleansing to see how well it works compared to control cleansing in preventing central line associated bloodstream infection and acquisition of multi-drug resistant organisms in younger patients with cancer or undergoing donor stem cell transplant. Chlorhexidine gluconate may help reduce bloodstream infections and bacterial infections associated with the central line.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBacterial Infection, Benign Neoplasm, Malignant Neoplasm, Methicillin-Resistant Staphylococcus Aureus Infection, Myeloid Neoplasm, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia
CountriesCanada, Puerto Rico, United States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 22, 2013
Enrollment StartNov 4, 2013
Primary CompletionMar 31, 2019
Study CompletionMar 31, 2020
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 13.3 years ago

Interventions

Chlorhexidine Gluconate Skin Cleanserprocedure

Given CHG cleansing

Laboratory Biomarker Analysisother

Correlative studies

Mild Soap Skin Cleanserprocedure

Given control cleansing

Questionnaire Administrationother

Ancillary studies