At a glance
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The Effects of Trazodone on the Severity of Obstructive Sleep Apnea
In Brief
A clinical study evaluating Placebo pill and Trazodone for Sleep Apnea, Obstructive. Completed, enrolled 15 participants across 1 site.
Detailed Summary
In Obstructive sleep apnea (OSA), the upper airway closes over and over again during sleep. This leads to disrupted sleep (waking up during the night), daytime sleepiness, and an increased risk for developing high blood pressure. Currently, the best treatment for obstructive sleep apnea is sleeping with a mask that continuously blows air into the nose (i.e. Continuous positive airway pressure \[CPAP\] treatment). While CPAP treatment stops the upper airway from closing in most people, many people have difficulty sleeping with the mask in place and therefore do not use the CPAP treatment. This research study is being conducted to learn whether using a sedative will improve OSA severity by altering some of the traits that are responsible for the disorder.
Study Details
Timeline
Interventions
Subjects will receive a sugar pill during the placebo arm
Subjects will receive trazodone during one of their treatment arm studies