CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 252 enrolled
Drug / intervention
E/C/F/TAFdrug
Likely dose
E/C/F/TAF 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01818596
NCT01818596Phase 3Completed

A Phase 3 Open-label Safety Study of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Single-Tablet Regimen in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

Gilead Sciences·interventional·Posted Mar 26, 2013·Updated Mar 2, 2020

In Brief

A Phase 3 clinical trial evaluating E/C/F/TAF for HIV and HIV Infections. Completed, enrolled 252 participants across 70 sites in 9 countries.

Detailed Summary

The primary objective of this study is to evaluate the effect of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) tablet on renal parameters at Week 24 in treatment-naive and treatment-experienced HIV-positive, adults with mild to moderate renal impairment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV, HIV Infections
CountriesAustralia, Dominican Republic, France, Mexico, Netherlands, Spain, Thailand, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 26, 2013
Enrollment StartMar 27, 2013
Primary CompletionJul 31, 2014
Study CompletionJul 18, 2018
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 13.3 years ago

Interventions

E/C/F/TAFdrug

E/C/F/TAF (150/150/200/10 mg) FDC tablet administered orally once daily with food