CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
Endodontic Regenerationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01827098
NCT01827098N/ACompleted
CompareCT.gov

A Randomized Controlled Clinical Trial of Regenerative Protocols to Treat Immature Necrotic Teeth

University of Michigan·interventional·Posted Apr 9, 2013·Updated Jul 11, 2023

In Brief

A clinical study evaluating Endodontic Regeneration for Dental Pulp Necrosis and Disorder of Tooth Development. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is induced four weeks later. The other method performs disinfection and induction of blood clot in one appointment. The investigators hypothesize that both methods will obtain the same success rate in eliminating infection, increase in root length and canal walls thickness.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Pulp Necrosis, Disorder of Tooth Development
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedApr 9, 2013
Enrollment StartOct 1, 2012
Primary CompletionJun 7, 2023
TodayJul 2, 2026
Enrollment to primary: 10.7 yearsPosted 13.2 years ago

Interventions

Endodontic Regenerationprocedure

Blood clot formation is induced in the root canal after disinfection. Collagen material is placed over the clot. The canal access is sealed with white MTA and glass ionomer restoration. Permanent restoration is placed 3 months later on top of the MTA.