At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase 2b, Multi-site, Randomized, Double-blind, Vehicle-controlled, Parallel-group Study Of The Efficacy, Safety, Local Tolerability And Pharmacokinetics Of 2 Dose Strengths And 2 Regimens Of Tofacitinib Ointment In Subjects With Chronic Plaque Psoriasis.
In Brief
A Phase 2 clinical trial evaluating tofacitinib ointment 20 mg/g, tofacitinib ointment 10 mg/g, and 1 other intervention for Psoriasis Vulgaris and Psoriasis. Completed, enrolled 476 participants across 54 sites in 4 countries.
Detailed Summary
The study is beng done to test if tofacitinib ointment is safe and effective for people with plaque psoriasis. Two dose strengths of tofacitinib ointment (20 mg/g and 10 mg/g) applied once or twice daily are being tested. The safety and effectiveness of tofacitinib ointment used for 12 weeks will be compared to the safety and effectiveness of placebo ointment (vehicle) used for 12 weeks.
Study Details
Timeline
Interventions
tofacitinib ointment 20 mg/g BID (twice daily) for 12 weeks
tofacitinib ointment 10 mg/g BID (twice daily) for 12 weeks
placebo ointment (vehicle) BID (twice daily) for 12 weeks
tofacitinib ointment 20 mg/g QD (once daily) for 12 weeks
tofacitinib ointment 10 mg/g QD (once daily) for 12 weeks
placebo ointment (vehicle) QD (once daily) for 12 weeks