CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 12 enrolled
Drug / intervention
Levothyroxinedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01832753
NCT01832753N/ACompleted
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Levothyroxine Treatment and Cardiometabolic Outcomes in Adolescents With Down Syndrome

Children's Hospital of Philadelphia·interventional·Posted Apr 16, 2013·Updated Sep 6, 2019

In Brief

A clinical study evaluating Levothyroxine for Down Syndrome and Subclinical Hypothyroidism. Completed, enrolled 12 participants across 2 sites.

Detailed Summary

The purpose of this research study is to learn about the effects of treating subclinical hypothyroidism (SCH) with thyroid hormone replacement in children and adolescents with Down syndrome (DS). We hypothesize that treatment of SCH with thyroid hormone replacement will improve cardiometabolic health and quality of life.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDown Syndrome, Subclinical Hypothyroidism
CountriesUnited States
CollaboratorsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedApr 16, 2013
Enrollment StartJan 1, 2013
Primary CompletionOct 18, 2017
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 13.2 years ago

Interventions

Levothyroxinedrug