CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 120 enrolled
Drug / intervention
Plavina creamdrug
Likely dose
Plavina cream 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01836393
NCT01836393Phase 3Completed
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Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 14% of Plai (Plaivana®) to Placebo Gels

Khon Kaen University·interventional·Posted Apr 19, 2013·Updated Apr 8, 2014

In Brief

A Phase 3 clinical trial evaluating Plavina cream for Knee Osteoarthritis. Completed, enrolled 120 participants across 2 sites.

Detailed Summary

To determine whether plai cream is effective in treating mild to moderate degrees of osteoarthritis of the knee in the elderly patient compared with placebo cream.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesThailand
Collaboratorsand Bangkok drugs Co.

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedApr 19, 2013
Enrollment StartJan 1, 2013
Primary CompletionJun 1, 2013
Study CompletionApr 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 13.2 years ago

Interventions

Plavina creamdrug

The essential plai cream has anti-inflammatory and antimicrobial effects (Wasuwat1989, Giwanon 2000, Pithayanukul 2007, and Tripathi 2008). Active chemicals of plai cream are composed of sabinene, alpha and gamma tepinenes, terpinen 4-ol and (E)-1-(3,4-dimethoxyphenyl butadiene (DMPBD). The DMPBD has a property of anti-inflammatory activity(Ozaki 1991, Jeenapongsa 2003). Plavina® 40 mg in 100 gm (contains DMPBD of …%). This product was supplied in lacquered aluminum collapsible tube containing 100 gram cream packing.