CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 32 enrolled
Drug / intervention
Gemcitabine +3 moredrug
Likely dose
Gemcitabine 1000mg/m2from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01839799
NCT01839799Phase 2Completed

A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma

Abramson Cancer Center at Penn Medicine·interventional·Posted Apr 25, 2013·Updated Feb 25, 2021

In Brief

A Phase 2 clinical trial evaluating Gemcitabine, Abraxane, and 2 other interventions for Pancreatic Adenocarcinoma. Completed, enrolled 32 participants across 1 site.

Detailed Summary

Determine the relapse-free survival of resected pancreatic cancer patients following two novel regimens with activity in advanced disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedApr 25, 2013
Enrollment StartApr 1, 2013
Primary CompletionApr 1, 2017
Study CompletionJul 1, 2017
TodayJul 2, 2026
Enrollment to primary: 4 yearsPosted 13.2 years ago

Interventions

Gemcitabinedrug

1000mg/m2 IV over 30 to 100 minutes, day 1, 8, 15

Abraxanedrug

125 mg/m2 IV over 30 minutes, day 1, 8, 15

FOLFIRINOXdrug

Irinotecan 180 mg/m2 Day 1 Oxaliplatin 85 mg/m2 Day 1 5-FU 400 mg/m2 bolus with Leucovorin 200 mg/m2 over 2h, Day 1, then 5-FU 2400 mg/m2 over 46h. Four cycles, if tolerated

Chemoradiationradiation