CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 72 enrolled
Drug / intervention
2x500 mg Metformin (Glumetza) +8 moredrug
Likely dose
5 mg Linagliptin/1000 mg Metformin FDCfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01845077
NCT01845077Phase 1Completed

Relative Bioavailability of Two Newly Developed Extended Release FDC Tablet Strengths (5mg/1000mg and 2.5 mg/750 mg) of Linagliptin/Metformin Extended Release Compared With the Free Combination of Linagliptin and Metformin Extended Release in Healthy Subjects (an Open-label, Randomised, Single Dose, Two-way Crossover Study)

Boehringer Ingelheim·interventional·Posted May 3, 2013·Updated Aug 19, 2014

In Brief

A Phase 1 clinical trial evaluating 2x500 mg Metformin (Glumetza), 5 mg Linagliptin/1000 mg Metformin FDC, and 5 other interventions for Healthy. Completed, enrolled 72 participants across 1 site.

Detailed Summary

The purpose of the trial is to demonstrate the relative bioavailability of 2 newly developed fixed dose combination (FDC) tablets containing linagliptin \& metformin and the single tablets of linagliptin and metformin when administered singularly.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States

Timeline

Phase 1CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMay 3, 2013
Enrollment StartMay 1, 2013
Primary CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 13.2 years ago

Interventions

2x500 mg Metformin (Glumetza)drug

2 tablets

5 mg Linagliptin/1000 mg Metformin FDCdrug

FDC tablet

5 mg Linagliptin (Tradjenta)drug

1 tablet

5 mg Linagliptin (Tradjenta)drug

1 tablet

3x500 mg Metformin (Glumetza)drug

3 tablets

5 mg Linagliptin (Tradjenta)drug

1 tablet

2 x 500 mg Metformin (Glumetza)drug

2 tablets

5 mg Linagliptin/1000mg Metformin FDCdrug

FDC Tablet

2 x 2.5 mg Linagliptin/750 mg Metformin FDCdrug

2 FDC tablets