At a glance
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Endoscopic Versus Open Radial Artery Harvest and Mammario-radial Versus Aorto-radial Grafting in Patients Undergoing Coronary Artery Bypass Surgery (The 2x2 Factorial Designed Randomised NEO Trial)
In Brief
A clinical study evaluating Endoscopic radial artery harvest, Open radial artery harvest, and 2 other interventions for Complications Due to Coronary Artery Bypass Graft and 8 related conditions. Completed, enrolled 301 participants across 1 site.
Detailed Summary
Coronary artery bypass grafting (CABG) using the radial artery (RA) has since the nineties gone through a revival. The initially reported worse outcome in RA graft patients compared to patients grafted with the saphenous vein (SV) has since been corrected. Studies have shown better patency when using RA, so the RA is going to be preferred more and more especially in younger patients where long time patency is critical. During the last 10 years endoscopic techniques to harvest the RA have evolved. Multiple different techniques have been used, but now the equipment and technique have been refined and are highly reliable. The investigators hypothesize that the endoscopic technique has less complications and a just as good patency as open harvest. There are also two possible ways to use the RA as a graft. One way is sewing it onto the aorta and another way is sewing it onto the mammarian artery. The investigators hypothesize that using it on the mammarian artery is superior as a revascularisation technique with just as good a patency as sewing it directly onto the aorta.
Study Details
Timeline
Interventions
Radial artery harvest is performed as an endoscopic procedure.
Radial artery harvest is performed as an open procedure.
The radial artery is used as an composite graft positioned on the internal mammarian artery.
The radial artery is used as an free graft positioned on the aorta.