At a glance
ClinicalIndex Comparison RecordN/ACompleted· 152 enrolled
Drug / intervention
Tranexamic Acid +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement; A Prospective Triple-blinded Randomized Controlled Trial.
In Brief
A clinical study evaluating Tranexamic Acid and Physiologic saline for Primary Osteoarthritis of Knee Nos. Completed, enrolled 152 participants across 1 site.
Detailed Summary
The purpose of this study is to determine 1) the effective dosage of intra-articular tranexamic acid injection for controlling blood loss and blood transfusion requirement in conventional total knee replacement, and 2) whether the blood loss reduction effect depended on the dose of tranexamic acid used.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrimary Osteoarthritis of Knee Nos
CountriesThailand
Collaborators--
Timeline
N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2010
Primary CompletionJan 2011
Study CompletionJan 2012
First PostedMay 2013
TodayJul 2026
First PostedMay 9, 2013
Enrollment StartJan 1, 2010
Primary CompletionJan 1, 2011
Study CompletionJan 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 13.1 years ago
Interventions
Tranexamic Aciddrug
Inject tranexamic acid solution intra-articularly after fascia closure
Physiologic salinedrug
Use physiologic saline for mixing with tranexamic acid or use alone in placebo group