At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma
In Brief
A Phase 2 clinical trial evaluating Dupilumab, placebo, and 3 other interventions for Asthma. Completed, enrolled 776 participants across 201 sites in 16 countries.
Detailed Summary
Primary Objective: To evaluate the efficacy of different doses and regimens of dupilumab in participants with moderate to severe uncontrolled asthma. Secondary Objective: To evaluate different doses and regimens of dupilumab in participants with moderate to severe uncontrolled asthma, with regard to: * Safety and tolerability * Dupilumab systemic exposure and anti-drug antibodies
Study Details
Timeline
Interventions
Solution for injection, Subcutaneous injection
Solution for injection, Subcutaneous injection
Oral inhalation, Prior therapy with Mometasone furoate /formoterol, budesonide / formoterol, or fluticasone propionate / salmeterol continued at stable dose
Oral inhalation as needed
Oral inhalation as needed