CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 38 enrolled
Drug / intervention
preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg) +1 moredrug
Likely dose
preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01857141
NCT01857141N/ACompleted
CompareCT.gov

Comparative Study on the Effects of Epidural Dexmedetomidine on Heart Rate Variability During General Anesthesia in Patients Undergoing Gastrectomy

Yonsei University·interventional·Posted May 20, 2013·Updated Feb 5, 2014

In Brief

A clinical study evaluating preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg) and normal saline for Gastric Cancer. Completed, enrolled 38 participants across 1 site.

Detailed Summary

The use of epidural dexmedetomidine decreases the anaesthetic requirements and improved postoperative pain. Dexmedetomidine is a potent and highly selective a2-adrenoceptor agonist and has sympatholytic effect. Power spectral analysis of heart rate variability(HRV) is a useful tool to assess cardiac autonomic activity. We investigated whether preemptive epidural dexmedetomidine can develop hemodynamic change and it could be identify patients by HRV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGastric Cancer
CountriesSouth Korea
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMay 20, 2013
Enrollment StartFeb 1, 2012
Primary CompletionJun 1, 2013
Study CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 13.1 years ago

Interventions

preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg)drug

Patients in the pre-emptive groups recived a dose of 1.5㎍/kg dexmedetomidine dissolved into normal saline 10cc before the induction of

normal salinedrug

patients in the control groups received the equivalent volume of normal saline.