CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 100 enrolled
Drug / intervention
Amoxicillin +2 moredrug
Likely dose
Amoxicillin 750mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01857804
NCT01857804Phase 4Completed
CompareCT.gov

Surgical Treatment of Peri-implantitis With and Without Adjunctive Use of Antibiotics : a Controlled and Randomized Clinical Study

Göteborg University·interventional·Posted May 20, 2013·Updated Nov 13, 2014

In Brief

A Phase 4 clinical trial evaluating Amoxicillin, Chlorhexidine gluconate, and 1 other intervention for Peri-Implantitis. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The objective of this randomized controlled clinical trial is to evaluate the outcome of treatment of peri-implantitis with or without systemic antibiotics. Specific aims are to analyze (i) the effect of systemic antibiotics and local antiseptics on the healing process, and (ii) the risk for recurrence of disease following surgical treatment of peri-implantitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeri-Implantitis
CountriesSweden
CollaboratorsThe Swedish Research Council

Timeline

Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMay 20, 2013
Enrollment StartJan 1, 2013
Primary CompletionNov 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 13.1 years ago

Interventions

Amoxicillindrug

In the test group a systemic antibiotic regimen will be initiated at 3 days before surgery and continued for 10 days. (2 x 750mg amoxicillin/day or 2 x 1g amoxicillin/day depending on the weight of the patient)

Chlorhexidine gluconatedrug

The exposed implant surfaces will be cleaned 3 minutes with antiseptics (chlorhexidine gluconate 0,2%) during the surgical treatment

Salinedrug

The exposed implant surfaces will be cleaned 3 minutes with saline during the surgical treatment