At a glance
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Assessing the Impact of Calcium Channel Blockers on COGnitive Function in the Very Elderly (AI-COG)
In Brief
An observational study for Cognitive Ability, General and High Blood Pressure. Completed, enrolled 337 participants across 7 sites.
Detailed Summary
Older adults are at increased risk of high blood pressure and cognitive decline. High blood pressure itself also increases risk of cognitive decline. A particular type of blood pressure lowering drug (a calcium channel blocker(CCB)) may lower risk of dementia in younger adults but there is no clear evidence of it's impact in those \>=80. It is important that we know whether CCB use impacts on cognitive function in this age group. This study will examine the impact of antihypertensives on change in cognitive function with a particular focus on CCBs.