CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 22 enrolled
Drug / intervention
11C-CSar +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01879735
NCT01879735Phase 1Completed
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Hepatic Transport of Conjugated Bile Acids in Humans Quantified by 11C-cholylsarcosine PET/CT

University of Aarhus·interventional·Posted Jun 18, 2013·Updated Feb 23, 2015

In Brief

A Phase 1 clinical trial evaluating 11C-CSar and ICG for Cholestasis and 2 related conditions. Completed, enrolled 22 participants across 1 site.

Detailed Summary

We wish to develop a protocol for PET/CT examination of humans using the bile acid tracer 11C-cholylsarcosine. This is done by a series of PET/CT examinations of healthy humans and patients with cholestatic disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCholestasis, Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis
CountriesDenmark
Collaborators--

Timeline

Phase 1CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 18, 2013
Enrollment StartJun 1, 2013
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 13.0 years ago

Interventions

11C-CSardrug

PET/CT recording with bile acid tracer 11C-cholylsarcosine used to evaluate the transport of bile acids.

ICGdrug

Infusion of indocyanine green prior and during the PET/CT scanning with the bile tracer 11C-CSar.