CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 395 enrolled
Drug / intervention
Tofacitinib +5 moredrug
Likely dose
Tofacitinib 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01882439
NCT01882439Phase 3Completed

A Phase 3, Randomized, Double-blind, Placebo-controlled Study Of The Efficacy And Safety Of 2 Doses Of Tofacitinib (Cp-690,550) In Subjects With Active Psoriatic Arthritis And An Inadequate Response To At Least One Tnf Inhibitor

Pfizer·interventional·Posted Jun 20, 2013·Updated Sep 15, 2017

In Brief

A Phase 3 clinical trial evaluating Tofacitinib and Placebo for Psoriatic Arthritis. Completed, enrolled 395 participants across 125 sites in 14 countries.

Detailed Summary

To examine the safety and efficacy of tofacitinib in subjects with active psoriatic arthritis who have previously had an inadequate response to at least one TNF inhibitor either due to lack of efficacy or an adverse event.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belgium, Brazil, Czechia, France, Germany, Mexico, Poland, Russia, Slovakia, Spain, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 20, 2013
Enrollment StartAug 1, 2013
Primary CompletionApr 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 13.0 years ago

Interventions

Tofacitinibdrug

tablets, 5 mg BID x 6 months

Tofacitinibdrug

tablets, 10 mg BID x 6 months

Placeboother

tablets, to match tofacitinib 5 mg BID x 3 months

Tofacitinibdrug

tablets, 5 mg BID x 3 months

Placeboother

tablets, to match tofacitinib 10 mg BID x 3 months

Tofacitinibdrug

tablets, 10 mg BID x 3 months