At a glance
ClinicalIndex Comparison RecordN/ACompleted· 5 enrolled
Drug / intervention
SCC DBSdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Deep Brain Stimulation for Treatment-Resistant Depression
In Brief
A clinical study evaluating SCC DBS for Treatment Resistant Depression and 2 related conditions. Completed, enrolled 5 participants across 1 site.
Detailed Summary
In this pilot study, we propose to test whether high frequency stimulation of the subcallosal cingulate (SCC) is a safe and efficacious antidepressant treatment in five TRD patients, to compare the effects of left-sided vs. right-sided stimulation, and to investigate potential mechanisms of action of this intervention. Importantly, this study will be used to assess the need for and assist in planning a larger, more definitive trial of SCC DBS for TRD.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTreatment Resistant Depression, Depressive Disorder, Treatment-Resistant, Depression, Bipolar
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
Enrollment StartJul 2013
First PostedJul 2013
Primary CompletionDec 2016
TodayJul 2026
First PostedJul 12, 2013
Enrollment StartJul 1, 2013
Primary CompletionDec 1, 2016
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 13.0 years ago
Interventions
SCC DBSdevice
Deep Brain Stimulator