CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 113 enrolled
Drug / intervention
Bronchoscopy +2 moreprocedure
Likely dose
Zinc sulfate 220 mg once dailyfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01899521
NCT01899521N/ACompleted
CompareCT.gov

Alcohol Abuse, Oxidative Stress, and Zinc Deficiency in Lung Disease

VA Office of Research and Development·interventional·Posted Jul 15, 2013·Updated Sep 19, 2024

In Brief

A clinical study evaluating Bronchoscopy, Zinc sulfate 220 mg once daily, and 1 other intervention for Alcoholism. Completed, enrolled 113 participants across 1 site.

Detailed Summary

This is a randomized, placebo controlled trial of dietary zinc and S-adenosylmethionine (SAMe) in otherwise healthy alcoholic US Veterans. The primary goal is to determine if either dietary zinc or S-adenosylmethionine (SAMe) can augment lung immune defenses in alcoholics and thereby decrease the risk of lung injury and infection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlcoholism
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 15, 2013
Enrollment StartMay 1, 2013
Primary CompletionJul 31, 2017
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 13.0 years ago

Interventions

Bronchoscopyprocedure

Involves flexible fiberoptic bronchoscopy with standardized bronchoalveolar lavage (BAL) technique (isotonic saline in a sub-segment of the right middle lobe or lingula) using standard conscious sedation techniques.

Zinc sulfate 220 mg once dailydietary

S-adenosylmethionine 400 mg twice dailydietary