CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 9 enrolled
Drug / intervention
Cocaine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01906346
NCT01906346Early Ph 1Completed
CompareCT.gov

Impact of a Non-Drug Choice on Cocaine Reinforcement

Joshua A. Lile, Ph.D.·interventional·Posted Jul 24, 2013·Updated May 17, 2019

In Brief

A Early Phase 1 clinical trial evaluating Cocaine and Placebo for Cocaine Dependence. Completed, enrolled 9 participants across 1 site.

Detailed Summary

Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-administration procedures and a non-drug alternative reinforcer, which is hypothesized to reduce the reinforcing effects of cocaine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Dependence
CountriesUnited States
Collaborators--

Timeline

Early Ph 1CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJul 24, 2013
Enrollment StartJan 1, 2014
Primary CompletionJun 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 12.9 years ago

Interventions

Cocainedrug

Three active doses of cocaine will be made available for self-administration during experimental sessions.

Placebodrug

Placebo cocaine will be made available for self-administration during experimental sessions.