CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 125 enrolled
Drug / intervention
Circadin 2/5/10 mg +1 moredrug
Likely dose
Circadin 2/5/10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01906866
NCT01906866Phase 3Completed

A Randomized, Placebo-controlled Study to Investigate the Efficacy and Safety of Circadin® to Alleviate Sleep Disturbances in Children With Neurodevelopmental Disabilities

Neurim Pharmaceuticals Ltd.·interventional·Posted Jul 24, 2013·Updated Apr 23, 2024

In Brief

A Phase 3 clinical trial evaluating Circadin 2/5/10 mg and Placebo for Sleep Disorders. Completed, enrolled 125 participants across 28 sites in 5 countries.

Detailed Summary

The purpose of this study is to establish the efficacy and safety of Circadin in children with neurodevelopmental disorders and to determine the dose, this randomized, placebo-controlled study is planned to evaluate the efficacy of a double-blind, 13 week treatment period with Circadin 2/5mg in improving maintenance of sleep, sleep latency and additional parameters in children with neurodevelopmental disabilities. The efficacy and safety of Circadin 2/5 mg will continue to be assessed during an open-label extension period of 13 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSleep Disorders
CountriesFinland, France, Netherlands, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJul 24, 2013
Enrollment StartOct 1, 2013
Primary CompletionMar 27, 2018
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 12.9 years ago

Interventions

Circadin 2/5/10 mgdrug

Circadin 2/5/10 mg. Active arm

Placebodrug

Control arm