At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 10 enrolled
Drug / intervention
Advair Diskus100/50 µg +3 moredrug
Likely dose
Advair Diskus100/50 µgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Dose-response of Salmeterol Delivered by Advair Diskus in Children: Bioassay by Methacholine Challenge Using Oscillometry as the Endpoint
In Brief
A Phase 4 clinical trial evaluating Advair Diskus100/50 µg, Flovent Diskus 100 µg, and 2 other interventions for Asthma. Completed, enrolled 10 participants across 1 site.
Detailed Summary
To examine whether a breathing test (methacholine challenge using impulse oscillometry) can be used to tell the difference between two different doses of an inhaled drug, salmeterol, delivered by Advair in children with asthma
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
CountriesUnited States
CollaboratorsTeva Branded Pharmaceutical Products R&D, Inc.
Timeline
Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJul 2013
Enrollment StartAug 2013
Primary CompletionMay 2014
Study CompletionJul 2014
TodayJul 2026
First PostedJul 24, 2013
Enrollment StartAug 1, 2013
Primary CompletionMay 1, 2014
Study CompletionJul 1, 2014
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 12.9 years ago
Interventions
Advair Diskus100/50 µgdrug
Advair Diskus 100/50 µg
Flovent Diskus 100 µgdrug
Flovent Diskus 100 µg
Methacholine Chloridedrug
Methacholine Chloride in quadrupling concentrations from 0.25 to 64 mg/mL will be given based upon subject's baseline response.
Albuteroldrug
Albuterol will be administered at the end of each methacholine challenge.