At a glance
ClinicalIndex Comparison RecordN/ACompleted· 53 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Multi-Center Study of the Prevalence of Known Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Variants and Functional Sucrase Activity by 13C-Sucrose Breath Test in Children With Chronic Diarrhea or Chronic Abdominal Pain
In Brief
An observational study for Congenital Sucrase-isomaltase Deficiency (CSID). Completed, enrolled 53 participants across 19 sites.
Detailed Summary
Congenital sucrose-isomaltase deficiency (CSID) is a rare, genetic disease in which mutations in the sucrose-isomaltase (SI) gene cause digestion problems of sucrose resulting in diarrhea and abdominal pain. Children with chronic, idiopathic diarrhea or abdominal pain will have their sucrose-isomaltase gene assessed for a panel of known CSID mutations to determine the prevalence of these mutations in an enriched population and also determine functional deficiency using a breath test.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsArnold Palmer Hospital for Children, Baylor College of Medicine, Nationwide Children's Hospital, Ann & Robert H Lurie Children's Hospital of Chicago, University of Mississippi Medical Center, Children's Hospital and Research Center at Oakland, Columbia University, Children's Hospital Los Angeles, Children's Hospital and Health System Foundation, Wisconsin, Children's Center for Digestive Healthcare, LLC, Massachusetts General Hospital, Duke University, Johns Hopkins University, Children's Hospital of Philadelphia, Children's Mercy Hospital Kansas City, Children's Hospital Colorado, Riley Children's Hospital, Primary Children's Hospital, State University of New York - Downstate Medical Center
Timeline
N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
Enrollment StartMay 2013
First PostedAug 2013
Primary CompletionMay 2015
Study CompletionJul 2015
TodayJul 2026
First PostedAug 1, 2013
Enrollment StartMay 1, 2013
Primary CompletionMay 1, 2015
Study CompletionJul 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 12.9 years ago