CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 59 enrolled
Drug / intervention
Trospium Chloride +1 moredrug
Likely dose
Trospium Chloride 60 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01922115
NCT01922115Phase 4Completed
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The Effect of Anticholinergics on Cognitive Function in the Elderly: a Randomized Controlled Trial

University of North Carolina, Chapel Hill·interventional·Posted Aug 14, 2013·Updated Mar 22, 2017

In Brief

A Phase 4 clinical trial evaluating Trospium Chloride and Placebo for Mental Competency and 2 related conditions. Completed, enrolled 59 participants across 1 site.

Detailed Summary

Anticholinergic medication is used to treat overactive bladder (OAB). A known side effect of this medication is cognitive dysfunction. OAB is more prevalent in the elderly population - a group that also has a higher baseline risk of cognitive dysfunction. Our objective is to evaluate the effect of an anticholinergic medication on cognitive function in elderly women.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMental Competency, Urinary Bladder, Overactive, Cognitive Function
CountriesUnited States
CollaboratorsAmerican Urogynecologic Society

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedAug 14, 2013
Enrollment StartJun 1, 2013
Primary CompletionJun 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 12.9 years ago

Interventions

Trospium Chloridedrug

Subject will be administered either placebo or 60 mg dosage of Sanctura XR for treatment of overactive bladder. Subject will take Sanctura XR once every morning. Blood will be drawn for plasma extraction at each visit.

Placebodrug