CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 6 enrolled
Drug / intervention
IST-16 (16-Channel implanted stimulator-telemeterdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01923662
NCT01923662N/ACompleted

Exploiting Selective Recruitment to Prolong Standing After SCI

VA Office of Research and Development·interventional·Posted Aug 15, 2013·Updated Aug 22, 2025

In Brief

A clinical study evaluating IST-16 (16-Channel implanted stimulator-telemeter for Spinal Cord Injury and 3 related conditions. Completed, enrolled 6 participants across 1 site.

Detailed Summary

The purpose of this study is to improve the performance of neuroprosthesis for standing after SCI by developing and testing new advanced methods that use multiple contact peripheral nerve electrodes to slow the onset of fatigue and increase standing duration. The new advanced methods will take advantage of the ability of multiple-contact nerve cuff electrodes to selectively activate portions of a muscle that perform the same action. Alternating activation to multiple muscles (or parts of the same muscle) rather than continuously activation the entire muscle group constantly should allow them to rest and recover from fatiguing contractions. This should allow users to remain upright for longer periods of time to perform activities of daily living, reduce the risk of falls due to fatigue, and increase the potential of receiving the health benefits of standing.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 15, 2013
Enrollment StartApr 11, 2013
Primary CompletionMar 18, 2024
TodayJul 2, 2026
Enrollment to primary: 10.9 yearsPosted 12.9 years ago

Interventions

IST-16 (16-Channel implanted stimulator-telemeterdevice

Surgical implantation of IST-16 stimulator and electrodes to stimulate paralyzed muscles. Subjects will receive exercise and physical therapy with the implanted device. Functional training and laboratory assessments of clinical and technical performance will be conducted.