At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pilot Study of Optiflow as a NIV Rest Therapy
In Brief
A clinical study evaluating High-flow humidified nasal oxygen delivery system and Standard oxygen therapy for Acute Respiratory Failure and Treatment With Noninvasive Positive Pressure Ventilation. Completed, enrolled 47 participants across 2 sites.
Detailed Summary
The purpose of this study is to assess whether Optiflow, a high-flow humidified oxygen delivery system, is superior to standard oxygen therapy during breaks off noninvasive ventilation in patients affected by acute respiratory failure and in respiratory distress. The investigators anticipate that the Optiflow will provide oxygen more effectively, be more comfortable and permit longer breaks off NIV, shortening the total duration of NIV.
Study Details
Timeline
Interventions
During breaks from NIV oxygen will be provided through the Optiflow with FiO2 and flow-rate titrated to maintain the oxygen saturation (SpO2) above 90%.
During breaks from NIV oxygen will be provided by standard nasal cannula or mask to maintain the SpO2 above 90%.