CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 589 enrolled
Drug / intervention
Varenicline for tobacco smoking cessation +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01926041
NCT01926041N/AActive

The Effectiveness of Smoking Cessation in Prediabetic Smokers

National Taiwan University Hospital·interventional·Posted Aug 20, 2013·Updated Jun 24, 2025

In Brief

A clinical study evaluating Varenicline for tobacco smoking cessation and Individualized counseling about both smoking cessation and weight control techniques for Diabetes Mellitus and 2 related conditions. Active but no longer recruiting, targeting 589 participants across 1 site.

Detailed Summary

Existing literature investigating the impact of smoking cessation on new-onset diabetes mellitus (DM) risk is conflicting. Combing the need for smoking cessation and body weight self-management to prevent the progression of prediabetes stage into DM, with the public implementation of the second-generation cessation program, we aimed to study the effectiveness of the Fight Tobacco and Stay Fit (FIT2) program aiming at promoting smoking cessation and restricting post-cessation weight gain (PCWG) together in prediabetic smokers regarding long-term glycemic and DM-related health outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTaiwan

Timeline

N/AActive
201420152016201720182019202020212022202320242025202620272028
First PostedAug 20, 2013
Enrollment StartAug 1, 2013
Primary CompletionDec 31, 2020
Study CompletionDec 31, 2027
TodayJul 2, 2026
Enrollment to primary: 7.4 yearsPosted 12.9 years ago

Interventions

Varenicline for tobacco smoking cessationdrug

The 16-week varenicline course conforms to real-practice government regulations in Taiwan.

Individualized counseling about both smoking cessation and weight control techniquesbehavioral

The FIT2 program also offers behavior coaching in diet and physical activity to restrict post-cessation weight gain, which is not covered in conventional smoking cessation services.