At a glance

ClinicalIndex Comparison Record

Phase 4Completed· 50 enrolled

Drug / intervention

rocuronium +2 moredrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01930747

NCT01930747Phase 4Completed

Compare CT.gov

Impact of Deep Neuromuscular Block Versus Inhalation and Total Intravenous Anesthesia (TIVA) on Laparoscopic Surgical Workspace Defined as Insufflated Pneumoperitoneum Volume.

AZ Sint-Jan AV·interventional·Posted Aug 29, 2013·Updated May 29, 2019

In Brief

A Phase 4 clinical trial evaluating rocuronium, Sevoflurane, and 1 other intervention for Muscle Relaxation. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The objective of this study is to compare the value of deep neuromuscular block (NMB) (using rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum alveolar concentration (MAC) inhalation (using sevoflurane) for the surgeon. The study hypothesis is that laparoscopic workspace is larger when using rocuronium versus opioids or inhalation. Laparoscopic workspace is measured as the abdominal compliance and the pressure at volume zero (PV0) using the abdominal pressure volume relation. Three points allow to calculate the abdominal compliance and the pressure at zero volume (PV0).

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsMuscle Relaxation

CountriesBelgium

Collaborators--

Timeline

Phase 4CompletedFinished

20132014201520162017201820192020202120222023202420252026

Enrollment StartApr 2013

First PostedAug 2013

Primary CompletionDec 2015

Study CompletionApr 2016

TodayJul 2026

First PostedAug 29, 2013

Enrollment StartApr 1, 2013

Primary CompletionDec 1, 2015

Study CompletionApr 1, 2016

TodayJul 2, 2026

Enrollment to primary: 2.7 yearsPosted 12.8 years ago

Interventions

rocuroniumdrug

measure effect on laparoscopic workspace

Sevofluranedrug

1 MAC sevoflurane inhalation is given

remifentanyldrug

remifentanyl is given in infusion