CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 5 enrolled
Drug / intervention
maxillary alveolar graft by tissue engineering +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01932164
NCT01932164N/ACompleted
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Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients

Hospital Sirio-Libanes·interventional·Posted Aug 30, 2013·Updated May 28, 2020

In Brief

A clinical study evaluating maxillary alveolar graft by tissue engineering and Bone tissue engineering using mesenchymal stem cells for Cleft Lip and Palate. Completed, enrolled 5 participants across 1 site.

Detailed Summary

The aim of this study is to perform the bone tissue engineering to reconstruct the alveolar bone defect in cleft lip and palate patients using mesenchymal stem cells from deciduous dental pulp associated with a collagen and hydroxyapatite biomaterial (Geistlich Bio-Oss®) through prospective qualitative and quantitative analysis of bone neoformation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCleft Lip and Palate
CountriesBrazil
CollaboratorsHospital Infantil Universitario Niño Jesús, Madrid, Spain

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 30, 2013
Enrollment StartMay 1, 2013
Primary CompletionDec 16, 2015
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 12.8 years ago

Interventions

maxillary alveolar graft by tissue engineeringprocedure

Extraction of deciduous teeth of cleft lip and palate patients to obtain mesenchymal stem cells;

Bone tissue engineering using mesenchymal stem cellsprocedure

Secondary alveolar graft in patients with cleft lip and palate using using mesenchymal stem cell obtained from dental pulp of deciduous teeth (autogenous) associated with a biomaterial composed of collagen and hydroxyapatite.