CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 81 enrolled
Drug / intervention
Docetaxel +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01932697
NCT01932697Phase 2Completed

Phase II Evaluation of Adjuvant Hyperfractionated Radiation and Docetaxel for HPV Associated Oropharynx Cancer

Mayo Clinic·interventional·Posted Aug 30, 2013·Updated Feb 10, 2026

In Brief

A Phase 2 clinical trial evaluating Docetaxel, Hyperfractionation, and 3 other interventions for Human Papillomavirus Infection and 5 related conditions. Completed, enrolled 81 participants across 2 sites.

Detailed Summary

This phase II trial studies how well radiation therapy and docetaxel work in treating patients with human papillomavirus (HPV)-related oropharyngeal cancer. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving radiation therapy with docetaxel my kill more tumor cells.

Study Details

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedAug 30, 2013
Enrollment StartSep 4, 2013
Primary CompletionOct 20, 2016
Study CompletionDec 28, 2021
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 12.8 years ago

Interventions

Docetaxeldrug

Given IV

Hyperfractionationradiation

Undergo hyperfractionated IMRT

Intensity-Modulated Radiation Therapyradiation

Undergo hyperfractionated IMRT

Laboratory Biomarker Analysisother

Correlative studies

Quality-of-Life Assessmentother

Ancillary studies