CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3 enrolled
Drug / intervention
Deep Brain Stimulation of the Lateral Hypothalamic Areadevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01933113
NCT01933113N/ACompleted
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Effects of Deep Brain Stimulation of the Lateral Hypothalamic Area on Weight Change and Metabolic Rate

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)·interventional·Posted Sep 2, 2013·Updated Oct 27, 2025

In Brief

A clinical study evaluating Deep Brain Stimulation of the Lateral Hypothalamic Area for Obesity. Completed, enrolled 3 participants across 1 site.

Detailed Summary

This study focuses on lateral hypothalamic area (LHA) deep brain stimulation (DBS) for severe obesity. In a previous pilot study, three subjects were implanted with a DBS electrode into the LHA under an Investigational Device Exemption (IDE) and IRB approved study at West Virginia University. That study demonstrated the safety of DBS of the LHA in these patients. These patients, who met the enrollment criteria of having prior placement of LHA DBS in accordance with previous study protocol, were eligible for this study with a goal of determining optimal DBS settings.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedSep 2, 2013
Enrollment StartAug 1, 2013
Primary CompletionJul 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 12.8 years ago

Interventions

Deep Brain Stimulation of the Lateral Hypothalamic Areadevice

Deep Brain Stimulation of the Lateral Hypothalamic Area