CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 64 enrolled
Drug / intervention
Pliaglis +2 moredrug
Likely dose
Pliaglis 0.2mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01951820
NCT01951820Phase 4Completed
CompareCT.gov

Comparison of Efficacy of Two Topical Anesthetics: Benzocaine Versus Pliaglis for Control of Pain Associated With Dental Needle Insertion in the Palate, A Double Blind Study

University of Michigan·interventional·Posted Sep 27, 2013·Updated Jul 22, 2016

In Brief

A Phase 4 clinical trial evaluating Pliaglis, Benzocaine, and 1 other intervention for Anesthesia of Mucous Membrane. Completed, enrolled 64 participants across 1 site.

Detailed Summary

The efficacy of the topical anesthetics will be determined by how much pain the patient felt (using a Heft-Parker pain analog scale) upon needle penetration.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnesthesia of Mucous Membrane
CountriesUnited States
CollaboratorsAmerican Association of Endodontists

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedSep 27, 2013
Enrollment StartAug 1, 2013
Primary CompletionJun 1, 2014
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 12.8 years ago

Interventions

Pliaglisdrug

Apply 0.2mg of compounded topical anesthetic (Pliaglis) to gums for 2.5 minutes before giving patient injection of local anesthetic.

Benzocainedrug

Apply 0.2mg of topical anesthetic (benzocaine) to gums for 2.5 minutes before giving patient injection of local anesthetic.

Articainedrug

Injection of 0.4mg of local anesthetic in gum tissue where topical anesthetic was placed