CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 5 enrolled
Drug / intervention
simvastatin +1 moredrug
Likely dose
simvastatin 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01952288
NCT01952288Phase 4Completed
CompareCT.gov

Simvastatin: Proof-of-Concept for Prevention of Neurodegeneration in Mild TBI

VA Office of Research and Development·interventional·Posted Sep 27, 2013·Updated Dec 15, 2021

In Brief

A Phase 4 clinical trial evaluating simvastatin and Placebo Oral Tablet for TBI-Traumatic Brain Injury. Completed, enrolled 5 participants across 1 site.

Detailed Summary

Study of simvastatin in Iraq/Afghanistan Veterans with multiple blast exposure and mTBI. The study will measure substances in cerebrospinal fluid (CSF) that are related to dementing disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTBI-Traumatic Brain Injury
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedSep 27, 2013
Enrollment StartSep 16, 2013
Primary CompletionJun 20, 2017
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 12.8 years ago

Interventions

simvastatindrug

simvastatin 40 mg/day for 12 months

Placebo Oral Tabletdrug

placebo comparator