CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 1,724 enrolled
Drug / intervention
Clopidogrel +4 moredrug
Likely dose
Clopidogrel 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01955200
NCT01955200Phase 4Completed
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Intensified Antiplatelet Therapy in Post-PCI Patients With High On-treatment Platelet Reactivity: the OPTIMA-2 Trial

The First Affiliated Hospital with Nanjing Medical University·interventional·Posted Oct 7, 2013·Updated Aug 18, 2020

In Brief

A Phase 4 clinical trial evaluating Clopidogrel, Cilostazol, and 1 other intervention for Coronary Artery Disease. Completed, enrolled 1,724 participants across 1 site.

Detailed Summary

High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary intervention (PCI). We sought to investigate the efficacy and safety of 1-month intensified antiplatelet therapies in post-PCI patients with HOPR.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease
CountriesChina
CollaboratorsNational Natural Science Foundation of China

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedOct 7, 2013
Enrollment StartOct 5, 2013
Primary CompletionDec 26, 2016
Study CompletionNov 28, 2017
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 12.7 years ago

Interventions

Clopidogreldrug

(ASA 100mg daily + Clopidogrel 150mg daily) x 1 month; (ASA 100mg daily + Clopidogrel 75mg daily) x 11 month.

Cilostazoldrug

(ASA 100mg daily + Clopidogrel 75mg daily + Cilostazol 150mg Bid) x 1 month; (ASA 100mg daily + Clopidogrel 75mg daily) x 11 month.

Ticagrelordrug

(ASA 100mg daily + Ticagrelor 90mg Bid) x 1 month; (ASA 100mg daily + Clopidogrel 75mg daily) x 11 month.

Clopidogreldrug

(ASA 100mg daily + Clopidogrel 75mg daily) x 12 month.

Clopidogreldrug

(ASA 100mg daily + Clopidogrel 75mg daily) x 12 month.