CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 50 enrolled
Drug / intervention
comparison of group-I (low dose propofol with isoflurane)drug
Likely dose
comparison of group-I (low dose propofol with isoflurane) 1 mg/Kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01958138
NCT01958138Phase 3Completed
CompareCT.gov

Isoflurane Versus Combination Of Propofol With Isoflurane For Removal Of Laryngeal Mask Airway In Children

Aga Khan University·interventional·Posted Oct 9, 2013·Updated Feb 15, 2021

In Brief

A Phase 3 clinical trial evaluating comparison of group-I (low dose propofol with isoflurane) for Complication of Anesthesia. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The study will be done in paediatric patients by comparing two different techniques of Laryngeal Mask Airway (LMA) removal under deep anesthetic plane. The both study techniques will be compared for safe LMA removal on the basis of adverse airway events and emergence time duration and recovery room stay timing.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsComplication of Anesthesia
CountriesPakistan
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedOct 9, 2013
Enrollment StartApr 1, 2012
Primary CompletionDec 1, 2012
Study CompletionNov 1, 2013
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 12.7 years ago

Interventions

comparison of group-I (low dose propofol with isoflurane)drug

Prior to LMA removal in group-I, isoflurane MAC awake (MAC less than 0.5) will be achieved in expiratory gases with 60% nitrous oxide and 40% oxygen. Propofol 1 mg/Kg will be combined with Isoflurane MAC awake and LMA will be removed after 20 seconds of propofol administration in group-I. The group-II LMA will be removed at end expiratory isoflurane MAC of 1.2% with 60% nitrous oxide and 40% oxygen