CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 184 enrolled
Drug / intervention
Loving-Kindness Meditation +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01962714
NCT01962714N/ACompleted
CompareCT.gov

A Trial of Loving-Kindness Meditation and Cognitive Processing Therapy for PTSD

VA Office of Research and Development·interventional·Posted Oct 14, 2013·Updated Mar 17, 2020

In Brief

A clinical study evaluating Loving-Kindness Meditation and Cognitive Processing Therapy for Posttraumatic Stress Disorder and Depression. Completed, enrolled 184 participants across 1 site.

Detailed Summary

This randomized controlled trial will assess whether a novel complementary and alternative medicines (CAM) intervention, Loving-kindness Meditation (LKM), is not meaningfully inferior to another group-based PTSD treatment , Cognitive Processing Therapy (Cognitive Only version; CPT-C) for reductions in PTSD and depressive symptoms. 170 male and female Veterans with current PTSD will be randomized to LKM or CPT-C. The investigators hypothesize that Veterans randomized to LKM will report mean reductions in PTSD and depressive symptom severity that are not meaningfully worse than CPT-C. The investigators further hypothesize that reductions in posttraumatic maladaptive beliefs will more strongly mediate PTSD and depressive symptom improvement for those assigned to CPT-C than those assigned to LKM.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPosttraumatic Stress Disorder, Depression
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedOct 14, 2013
Enrollment StartDec 1, 2014
Primary CompletionNov 29, 2018
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 12.7 years ago

Interventions

Loving-Kindness Meditationbehavioral

12-week loving-kindness meditation course

Cognitive Processing Therapybehavioral

12-week CPT course