CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 23 enrolled
Drug / intervention
Concurrent chemotherapy (Gemcitabine, Capecitabine) +1 moredrug
Likely dose
Concurrent chemotherapy (Gemcitabine, Capecitabine) 400mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01972919
NCT01972919Phase 2Active
CompareCT.gov

MR Guided Phase II Radiotherapy Dose Escalation in Unresectable Non-metastatic Pancreatic Cancer

Medical College of Wisconsin·interventional·Posted Oct 31, 2013·Updated May 12, 2026

In Brief

A Phase 2 clinical trial evaluating Radiation Therapy and Concurrent chemotherapy (Gemcitabine, Capecitabine) for Unresectable Pancreatic Cancer. Active but no longer recruiting, targeting 23 participants across 1 site.

Detailed Summary

This research study is for people who have pancreas cancer for which surgery is not recommended. Potential patients must have already received several months of chemotherapy before they are eligible for this study and there will not have been any detectable spread of their tumor on imaging studies following this chemotherapy course.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUnresectable Pancreatic Cancer
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
20142015201620172018201920202021202220232024202520262027
First PostedOct 31, 2013
Enrollment StartDec 10, 2015
Primary CompletionDec 13, 2023
Study CompletionNov 1, 2026
TodayJul 2, 2026
Enrollment to primary: 8.0 yearsPosted 12.7 years ago

Interventions

Radiation Therapyradiation

Radiation therapy dose escalation to an MR-defined gross tumor volume (GTV) of up to 69.75 Gy at 2.25 Gy per fraction.

Concurrent chemotherapy (Gemcitabine, Capecitabine)drug

Gemcitabine 400mg/m\^2 IV weekly x 6 doses. Capecitabine 825 mg/m\^2 by mouth twice daily Monday-Friday on days of radiation use 500 mg tablets.