At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 5,774 enrolled
Drug / intervention
Propofol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer
In Brief
A Phase 4 clinical trial evaluating Propofol and Sevoflurane for Breast Neoplasms and 2 related conditions. Completed, enrolled 5,774 participants across 15 sites in 3 countries.
Detailed Summary
The purpose of this study is to determine whether anesthesia maintained with propofol results in better one- and five-year-survival than anesthesia maintained with sevoflurane.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Neoplasms, Colonic Neoplasms, Rectal Neoplasms
CountriesChina, Poland, Sweden
CollaboratorsRegion Örebro County, University Hospital, Linkoeping, Lund University Hospital, Kalmar County Hospital, Skellefteå lasarett, Wroclaw Medical University, Sundsvall Hospital, Peking University First Hospital, Helsingborgs Hospital, Air Force Military Medical University, China, RenJi Hospital, Uppsala University Hospital, University Hospital Sestre Milosrdnice, Växjö Hospital
Timeline
Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
Enrollment StartNov 2013
First PostedNov 2013
Primary CompletionAug 2022
TodayJul 2026
First PostedNov 4, 2013
Enrollment StartNov 1, 2013
Primary CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 8.8 yearsPosted 12.7 years ago
Interventions
Propofoldrug
Propofol will be infused individually for a sufficient level of anesthesia during the entire surgical procedure.
Sevofluranedrug
Sevoflurane will be administered by vaporizer individually for a sufficient level of anesthesia during the entire surgical procedure.