CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled
Drug / intervention
Sodium Nitrate +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01983826
NCT01983826N/ACompleted
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Dietary Nitrates and Vascular Function in Patients With Peripheral Artery Disease

University of Iowa·interventional·Posted Nov 14, 2013·Updated Jun 3, 2019

In Brief

A clinical study evaluating Sodium Nitrate and Placebo for Peripheral Artery Disease. Completed, enrolled 21 participants across 1 site.

Detailed Summary

The overarching question addressed in the current project is: Does dietary nitrate supplementation (8 weeks) improve physiological function in patients with peripheral arterial disease (PAD)? The investigators will specifically address whether dietary nitrate supplementation enhances blood vessel function, blood pressure regulation, and exercise capacity. The proposed project uses an array of clearly defined measurements which will allow investigators to quantify blood vessel function (vasodilator responsiveness and arterial stiffness), blood pressure (variability and responsiveness to stress), and functional capacity before and after 8 weeks of dietary supplementation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeripheral Artery Disease
CountriesUnited States
CollaboratorsAmerican Heart Association

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedNov 14, 2013
Enrollment StartNov 1, 2013
Primary CompletionJun 30, 2016
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 12.6 years ago

Interventions

Sodium Nitratedietary

Sodium Nitrate (1g/day) for 8 weeks

Placeboother

Microcrystalline cellulose (daily) for 8 weeks