CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 364 enrolled
Drug / intervention
APD421- Amisulpride for IV injection +1 moredrug
Likely dose
APD421- Amisulpride for IV injection 5mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01991860
NCT01991860Phase 3Completed

Randomized, Double-blind, Placebo-controlled Phase III Study of APD421 (Amisulpride for IV Injection) as Prophylaxis Against Post-operative Nausea and Vomiting

Acacia Pharma Ltd·interventional·Posted Nov 25, 2013·Updated Feb 12, 2019

In Brief

A Phase 3 clinical trial evaluating APD421- Amisulpride for IV injection and Placebo for PONV. Completed, enrolled 364 participants across 1 site.

Detailed Summary

A comparison of the efficacy of APD421 and placebo in the prevention of PONV in patients at moderate-to-high risk of PONV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPONV
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedNov 25, 2013
Enrollment StartAug 1, 2013
Primary CompletionJan 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 12.6 years ago

Interventions

APD421- Amisulpride for IV injectiondrug

APD421 ( Amisulpride) at 5mg given by single intravenous (IV) administration, by slow push over one minute, at induction of anaesthesia

Placebodrug

Matching Placebo given by single intravenous (IV) administration, by slow push over one minute, at induction of anaesthesia