At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Control of Cognition: Naltrexone, Methylphenidate, and ADHD Study
In Brief
A Phase 4 clinical trial evaluating Methylphenidate, Naltrexone, and 1 other intervention for Healthy and Attention Deficit Hyperactivity Disorder. Completed, enrolled 23 participants across 1 site.
Detailed Summary
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits. This research study will use a scanning technique known as functional magnetic resonance imaging (fMRI) which takes a special kind of picture of the brain that enables us to "see the brain at work". Adult participants will be given a one-time dose of either methylphenidate, naltrexone,or placebo before each fMRI scan session. The main purpose for this research is to better understand the functioning of regulatory circuits in healthy individuals and individuals with psychiatric disorders. This research may one day help us develop better treatments for these disorders.
Study Details
Timeline
Interventions
One dose 40mgs of methylphenidate one hour before fMRI scanning.
One dose 40mgs of naltrexone one hour before fMRI scanning.
One dose of placebo one hour before fMRI scanning.