CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 509 enrolled
Drug / intervention
Enzalutamide +3 moredrug
Likely dose
Enzalutamide 160 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01995513
NCT01995513Phase 4Completed

A PHASE 4, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF CONTINUED ENZALUTAMIDE TREATMENT BEYOND PROGRESSION IN PATIENTS WITH CHEMOTHERAPY-NAÏVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

Pfizer·interventional·Posted Nov 26, 2013·Updated Sep 18, 2023

In Brief

A Phase 4 clinical trial evaluating Enzalutamide, Abiraterone, and 2 other interventions for Prostate Cancer. Completed, enrolled 509 participants across 95 sites in 11 countries.

Detailed Summary

The purpose of this study is to determine if continued treatment with Enzalutamide is effective in patients with metastatic prostate cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstate Cancer
CountriesAustralia, Belgium, Denmark, Finland, France, Italy, Slovakia, Spain, Sweden, United Kingdom, United States

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedNov 26, 2013
Enrollment StartOct 22, 2013
Primary CompletionNov 15, 2016
Study CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 12.6 years ago

Interventions

Enzalutamidedrug

160 mg by mouth once daily

Abirateronedrug

1000 mg by mouth once daily

Placebo for Enzalutamidedrug

Sugar pill manufactured to mimic Enzalutamide 40 mg capsule

Prednisonedrug

5 mg by mouth twice daily