At a glance
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A Phase II Study for the Treatment of Non-metastatic Nodular Desmoplastic Medulloblastoma in Children Less Than 4 Years of Age
In Brief
A Phase 2 clinical trial evaluating Carboplatin, Cognitive Assessment, and 5 other interventions for Desmoplastic/Nodular Medulloblastoma and 3 related conditions. Completed, enrolled 26 participants across 173 sites in 4 countries.
Detailed Summary
This phase II trial studies how well combination chemotherapy works in treating younger patients with newly diagnosed, non-metastatic desmoplastic medulloblastoma. Drugs used in chemotherapy, such as vincristine sulfate, cyclophosphamide, methotrexate, etoposide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Study Details
Timeline
Interventions
Given IV
Optional ancillary studies
Given IV
Given IV
Correlative studies
Given IV
Given IV