CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 2,590 enrolled
Drug / intervention
Aspirin+Ticagrelor +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02018055
NCT02018055Phase 4Completed
CompareCT.gov

A Prospective, Multicenter, Randomized, Open-label Trial to Compare Efficacy and Safety of Clopidogrel vs Ticagrelor in Stabilized Patients With Acute Myocardial Infarction After Percutaneous Coronary Intervention; TicAgrelor Versus CLOpidogrel in Stabilized Patients With Acute Myocardial Infarction: TALOS-AMI

The Catholic University of Korea·interventional·Posted Dec 23, 2013·Updated Apr 2, 2021

In Brief

A Phase 4 clinical trial evaluating Aspirin+Ticagrelor and Aspirin+Clopidogrel for Acute Myocardial Infarction. Completed, enrolled 2,590 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the efficacy and safety of clopidogrel in stabilized patients with acute myocardial infarction (AMI) who performed percutaneous coronary intervention (PCI) with drug-eluting stents (DES) compared with ticagrelor. In this study, 2,590 patients with AMI who underwent PCI with DES and took dual antiplatelet therapy as aspirin and ticagrelor during 1 month from index PCI will be randomized to aspirin+ticagrelor versus aspirin+ clopidogrel during 11 months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Myocardial Infarction
CountriesSouth Korea
CollaboratorsChonnam National University Hospital

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedDec 23, 2013
Enrollment StartFeb 14, 2014
Primary CompletionJan 21, 2021
TodayJul 2, 2026
Enrollment to primary: 6.9 yearsPosted 12.5 years ago

Interventions

Aspirin+Ticagrelordrug

Aspirin+ Ticagrelor after 1month of standard DAPT (Aspirin+Ticagrelor)

Aspirin+Clopidogreldrug

Aspirin+ Clopidogrel after 1month of standard DAPT (Aspirin+Ticagrelor)