CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 27 enrolled
Drug / intervention
Coagulation Factor VIIa (Recombinant)biological
Likely dose
Coagulation Factor VIIa (Recombinant) 75µgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02020369
NCT02020369Phase 3Completed

A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors to Factor VIII or IX

rEVO Biologics·interventional·Posted Dec 24, 2013·Updated Jun 14, 2017

In Brief

A Phase 3 clinical trial evaluating Coagulation Factor VIIa (Recombinant) for Hemophilia A With Inhibitors and Hemophilia B With Inhibitors. Completed, enrolled 27 participants across 17 sites in 10 countries.

Detailed Summary

The purpose of the study is to assess the safety, efficacy and pharmacokinetics of 2 separate dose regimens (75µg/kg and 225 µg/kg) of Coagulation Factor VIIa (Recombinant) for the treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII/IX

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelarus, Bulgaria, Georgia, Israel, Poland, Romania, Russia, Ukraine, United Kingdom, United States

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedDec 24, 2013
Enrollment StartApr 1, 2014
Primary CompletionJul 1, 2015
Study CompletionAug 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 12.5 years ago

Interventions

Coagulation Factor VIIa (Recombinant)biological

A cross over design to assess the efficacy of 2 separate dose regimens (75µg/kg and 225 µg/kg) of Coagulation Factor VIIa (Recombinant) for the treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII/IX